Pharmacokinetics and pharmacodynamics of a new reformulated microemulsion and the long-chain triglyceride emulsion of propofol in beagle dogs

BACKGROUND AND PURPOSE: Microemulsion propofol was developed to eliminate lipid solvent-related adverse events of long-chain triglyceride emulsion (LCT) propofol. We compared dose proportionality, pharmacokinetic and pharmacodynamic characteristics of both formulations. EXPERIMENTAL APPROACH: The st...

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Autores principales: Lee, S-H, Ghim, J-L, Song, M-H, Choi, H-G, Choi, B-M, Lee, H-M, Lee, E-K, Roh, Y-J, Noh, G-J
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2009
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807660/
https://ncbi.nlm.nih.gov/pubmed/19925493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00509.x
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