Thromboelastographic and Pharmacokinetic Profiles of Micro- and Macro-emulsions of Propofol in the Swine

PURPOSE: Compared to traditional macroemulsion propofol formulations currently in clinical use, microemulsion formulations of this common intravenous anesthetic may offer advantages. We characterized the pharmacokinetics and coagulation effects as assessed by thromboelastography of these formulation...

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Main Authors: Morey, Timothy E., Modell, Jerome H., Garcia, Jorge E., Bewernitz, Michael, Derendorf, Hartmut, Varshney, Manoj, Gravenstein, Nikolaus, Shah, Dinesh O., Dennis, Donn M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021748/
https://ncbi.nlm.nih.gov/pubmed/20578214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.709
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