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Together, Rpn10 and Dsk2 can serve as a polyubiquitin chain-length sensor
As a signal for substrate targeting, polyubiquitin meets various layers of receptors upstream to the 26S proteasome. We obtained structural information on two receptors, Rpn10 and Dsk2, alone, and in complex with (poly)ubiquitin or with each other. A hierarchy of affinities emerges with Dsk2 binding...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807407/ https://ncbi.nlm.nih.gov/pubmed/20064467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.11.012 |
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