Novel sequence feature variant type analysis of the HLA genetic association in systemic sclerosis

We describe a novel approach to genetic association analyses with proteins sub-divided into biologically relevant smaller sequence features (SFs), and their variant types (VTs). SFVT analyses are particularly informative for study of highly polymorphic proteins such as the human leukocyte antigen (H...

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Detalhes bibliográficos
Main Authors: Karp, David R., Marthandan, Nishanth, Marsh, Steven G.E., Ahn, Chul, Arnett, Frank C., DeLuca, David S., Diehl, Alexander D., Dunivin, Raymond, Eilbeck, Karen, Feolo, Michael, Guidry, Paula A., Helmberg, Wolfgang, Lewis, Suzanna, Mayes, Maureen D., Mungall, Chris, Natale, Darren A., Peters, Bjoern, Petersdorf, Effie, Reveille, John D., Smith, Barry, Thomson, Glenys, Waller, Matthew J., Scheuermann, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807365/
https://ncbi.nlm.nih.gov/pubmed/19933168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp521
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