ERK Regulates Calpain 2-induced Androgen Receptor Proteolysis in CWR22 Relapsed Prostate Tumor Cell Lines

Androgen ablation therapy is effective in treating androgen-dependent prostate tumors; however, tumors that can proliferate in castrate levels of androgen eventually arise. We previously reported that in CWR22Rv1 (Rv1) cells, the protease calpain 2 can cleave the androgen receptor (AR) into a consti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Honglin, Libertini, Stephen J., Wang, Yu, Kung, Hsing-Jien, Ghosh, Paramita, Mudryj, Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Protein Synthesis, Post-Translational Modification, and Degradation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807295/
https://ncbi.nlm.nih.gov/pubmed/19946123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049379
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