Liver-Specific Ablation of Integrin-Linked Kinase in Mice Results in Enhanced and Prolonged Cell Proliferation and Hepatomegaly after Phenobarbital Administration

We have recently demonstrated that disruption of extracellular matrix (ECM)/integrin signaling via elimination of integrin-linked kinase (ILK) in hepatocytes interferes with signals leading to termination of liver regeneration. This study investigates the role of ILK in liver enlargement induced by...

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Auteurs principaux: Donthamsetty, Shashikiran, Bowen, William, Mars, Wendy, Bhave, Vishakha, Luo, Jian-Hua, Wu, Cary, Hurd, Jennifer, Orr, Ann, Bell, Aaron, Michalopoulos, George
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2010
Sujets:
Carcinogenicity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807039/
https://ncbi.nlm.nih.gov/pubmed/19920070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp281
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