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Crystal Structure of the S. solfataricus Archaeal Exosome Reveals Conformational Flexibility in the RNA-Binding Ring

BACKGROUND: The exosome complex is an essential RNA 3′-end processing and degradation machinery. In archaeal organisms, the exosome consists of a catalytic ring and an RNA-binding ring, both of which were previously reported to assume three-fold symmetry. METHODOLOGY/PRINCIPAL FINDINGS: Here we repo...

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Autores principales: Lu, Changrui, Ding, Fang, Ke, Ailong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806925/
https://ncbi.nlm.nih.gov/pubmed/20090900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008739
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