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Genetic modeling of Li-Fraumeni syndrome in zebrafish
Li-Fraumeni syndrome (LFS) is a highly penetrant, autosomal dominant, human familial cancer predisposition. Although a key role for the tumor suppressor p53 has been implicated in LFS, the genetic and cellular mechanisms underpinning this disease remain unknown. Therefore, modeling LFS in a vertebra...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Company of Biologists Limited
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806900/ https://ncbi.nlm.nih.gov/pubmed/20075382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.003749 |
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