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TRPC3 Channels Are Necessary for Brain-Derived Neurotrophic Factor to Activate a Nonselective Cationic Current and to Induce Dendritic Spine Formation

Brain-derived neurotrophic factor (BDNF) exerts prominent effects on hippocampal neurons, but the mechanisms that initiate its actions are poorly understood. We report here that BDNF evokes a slowly developing and sustained nonselective cationic current (I(BDNF)) in CA1 pyramidal neurons. These resp...

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Bibliografiske detaljer
Main Authors: Amaral, Michelle D., Pozzo-Miller, Lucas
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806846/
https://ncbi.nlm.nih.gov/pubmed/17494704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5499-06.2007
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