Niche recycling through division-independent egress of hematopoietic stem cells

Hematopoietic stem cells (HSCs) are thought to reside in discrete niches through stable adhesion, yet previous studies have suggested that host HSCs can be replaced by transplanted donor HSCs, even in the absence of cytoreductive conditioning. To explain this apparent paradox, we calculated, through...

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Main Authors: Bhattacharya, Deepta, Czechowicz, Agnieszka, Ooi, A.G. Lisa, Rossi, Derrick J., Bryder, David, Weissman, Irving L.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806613/
https://ncbi.nlm.nih.gov/pubmed/19887396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090778
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