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Rupintrivir is a promising candidate for treating severe cases of Enterovirus-71 infection

AIM: To evaluate the suitability of rupintrivir against Enterovirus 71 (EV71) induced severe clinical symptoms using computational methods. METHODS: The structure of EV71 3C protease was predicted by homology modeling. The binding free energies between rupintrivir and EV71 3C and human rhinovirus 3C...

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Autors principals: Zhang, Xiao-Nan, Song, Zhi-Gang, Jiang, Ting, Shi, Bi-Sheng, Hu, Yun-Wen, Yuan, Zheng-Hong
Format: Artigo
Idioma:Inglês
Publicat: Baishideng 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806558/
https://ncbi.nlm.nih.gov/pubmed/20066739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i2.201
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