HLA-B*35-Px–mediated acceleration of HIV-1 infection by increased inhibitory immunoregulatory impulses

A subset of HLA-B*35 alleles, B*35-Px, are strongly associated with accelerated HIV-1 disease progression for reasons that are not understood. Interestingly, the alternative set of B*35 subtypes, B*35-PY, have no detectable impact on HIV-1 disease outcomes, even though they can present identical HIV...

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Autores principales: Huang, Jinghe, Goedert, James J., Sundberg, Eric J., Cung, Thai Duong Hong, Burke, Patrick S., Martin, Maureen P., Preiss, Liliana, Lifson, Jeffrey, Lichterfeld, Mathias, Carrington, Mary, Yu, Xu G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2009
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806456/
https://ncbi.nlm.nih.gov/pubmed/20008523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091386
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