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Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity

TRPM2 is a Ca(2+)-permeable nonselective cation channel that plays important roles in oxidative stress–mediated cell death and inflammation processes. However, how TRPM2 is regulated under physiological and pathological conditions is not fully understood. Here, we report that both intracellular and...

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Detalles Bibliográficos
Main Authors: Du, Jianyang, Xie, Jia, Yue, Lixia
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806426/
https://ncbi.nlm.nih.gov/pubmed/19917732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910254
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