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Intracellular calcium activates TRPM2 and its alternative spliced isoforms
Melastatin-related transient receptor potential channel 2 (TRPM2) is a Ca(2+)-permeable, nonselective cation channel that is involved in oxidative stress-induced cell death and inflammation processes. Although TRPM2 can be activated by ADP-ribose (ADPR) in vitro, it was unknown how TRPM2 is gated in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678461/ https://ncbi.nlm.nih.gov/pubmed/19372375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811725106 |
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