E2F1-3 Switch from Activators in Progenitor Cells to Repressors in Differentiating Cells

In the classic paradigm of mammalian cell cycle control, Rb functions to restrict cells from entering S phase by sequestering E2F activators (E2f1, E2f2 and E2f3), which are invariably portrayed as the ultimate effectors of a transcriptional program that commit cells to enter and progress through S...

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Main Authors: Chong, Jean-Leon, Wenzel, Pamela L., Sáenz-Robles, M. Teresa, Nair, Vivek, Ferrey, Antoney, Hagan, John P., Gomez, Yorman M., Sharma, Nidhi, Chen, Hui-Zi, Ouseph, Madhu, Wang, Shu-Huei, Trikha, Prashant, Culp, Brian, Mezache, Louise, Winton, Douglas J., Sansom, Owen J., Chen, Danian, Bremner, Rod, Cantalupo, Paul G., Robinson, Michael L., Pipas, James M., Leone, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806193/
https://ncbi.nlm.nih.gov/pubmed/20016602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08677
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