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Rb-Mediated Neuronal Differentiation through Cell-Cycle–Independent Regulation of E2f3a

It has long been known that loss of the retinoblastoma protein (Rb) perturbs neural differentiation, but the underlying mechanism has never been solved. Rb absence impairs cell cycle exit and triggers death of some neurons, so differentiation defects may well be indirect. Indeed, we show that abnorm...

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Bibliografski detalji
Glavni autori: Chen, Danian, Opavsky, Rene, Pacal, Marek, Tanimoto, Naoyuki, Wenzel, Pamela, Seeliger, Mathias W, Leone, Gustavo, Bremner, Rod
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914394/
https://ncbi.nlm.nih.gov/pubmed/17608565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050179
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