Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8

Gene activation and repression regulated by acetylation and deacetylation represent a paradigm for the function of histone modifications. We provide evidence that, in contrast, histone H2B monoubiquitylation and its deubiquitylation are both involved in gene activation. Substitution of the H2B ubiqu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genes Dev
Päätekijät: Henry, Karl W., Wyce, Anastasia, Lo, Wan-Sheng, Duggan, Laura J., Emre, N.C. Tolga, Kao, Cheng-Fu, Pillus, Lorraine, Shilatifard, Ali, Osley, Mary Ann, Berger, Shelley L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2003
Aiheet:
Research Papers
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280615/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14563679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1144003
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