Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8

Gene activation and repression regulated by acetylation and deacetylation represent a paradigm for the function of histone modifications. We provide evidence that, in contrast, histone H2B monoubiquitylation and its deubiquitylation are both involved in gene activation. Substitution of the H2B ubiqu...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Henry, Karl W., Wyce, Anastasia, Lo, Wan-Sheng, Duggan, Laura J., Emre, N.C. Tolga, Kao, Cheng-Fu, Pillus, Lorraine, Shilatifard, Ali, Osley, Mary Ann, Berger, Shelley L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Cold Spring Harbor Laboratory Press 2003
Θέματα:
Research Papers
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC280615/
https://ncbi.nlm.nih.gov/pubmed/14563679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1144003
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