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Noncanonical TGF-β pathways, mTORC1 and Abl, in renal interstitial fibrogenesis
Renal interstitial fibrosis is a major determinant of renal failure in the majority of chronic renal diseases. Transforming growth factor-β (TGF-β) is the single most important cytokine promoting renal fibrogenesis. Recent in vitro studies identified novel non-smad TGF-β targets including p21-activa...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806113/ https://ncbi.nlm.nih.gov/pubmed/19846571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00320.2009 |
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