Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity

Insulin resistance in skeletal muscle in obesity and T2DM is associated with reduced muscle oxidative capacity, reduced expression in nuclear genes responsible for oxidative metabolism, and reduced activity of mitochondrial electron transport chain. The presented study was undertaken to analyze mito...

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Detalhes bibliográficos
Main Authors: Ritov, Vladimir B., Menshikova, Elizabeth V., Azuma, Koichiro, Wood, Richard, Toledo, Frederico G. S., Goodpaster, Bret H., Ruderman, Neil B., Kelley, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806111/
https://ncbi.nlm.nih.gov/pubmed/19887598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00317.2009
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