Skeletal muscle NAMPT is induced by exercise in humans

In mammals, nicotinamide phosphoribosyltransferase (NAMPT) is responsible for the first and rate-limiting step in the conversion of nicotinamide to nicotinamide adenine dinucleotide (NAD(+)). NAD(+) is an obligate cosubstrate for mammalian sirtuin-1 (SIRT1), a deacetylase that activates peroxisome p...

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Main Authors: Costford, Sheila R., Bajpeyi, Sudip, Pasarica, Magdalena, Albarado, Diana C., Thomas, Shantele C., Xie, Hui, Church, Timothy S., Jubrias, Sharon A., Conley, Kevin E., Smith, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806106/
https://ncbi.nlm.nih.gov/pubmed/19887595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00318.2009
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