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Skeletal muscle NAMPT is induced by exercise in humans
In mammals, nicotinamide phosphoribosyltransferase (NAMPT) is responsible for the first and rate-limiting step in the conversion of nicotinamide to nicotinamide adenine dinucleotide (NAD(+)). NAD(+) is an obligate cosubstrate for mammalian sirtuin-1 (SIRT1), a deacetylase that activates peroxisome p...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806106/ https://ncbi.nlm.nih.gov/pubmed/19887595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00318.2009 |
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