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"Shping 2" different cellular localizations - a potential new player in aging processes

The functions of the ubiquitously expressed protein tyrosine phosphatase Shp-2 are dependent on its localization. Cytosolic Shp-2 is known to modulate different pathways involved in cell growth, cell development, tissue inflammation and cellular chemotaxis. But Shp-2 is also localized in the nucleus...

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Autori principali: Jakob, Sascha, Altschmied, Joachim, Haendeler, Judith
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806037/
https://ncbi.nlm.nih.gov/pubmed/20157547
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