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Ca(2+)-dependent photocrosslinking of tropomyosin residue 146 to residues 157-163 in the C-terminal domain of troponin I in reconstituted skeletal muscle thin filaments

The Ca(2+)-dependent interaction of troponin I (TnI) with actin•tropomyosin (Actin•Tm) in the muscle thin filament is a critical step in the regulation of muscle contraction. Previous studies have suggested that, in the absence of Ca(2+), TnI interacts with Tm as well as actin in the reconstituted m...

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Autors principals: Mudalige, Wasana A.K.A., Tao, Terence C., Lehrer, Sherwin S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805953/
https://ncbi.nlm.nih.gov/pubmed/19379756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.027
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