Long-term Temozolomide Treatment Induces Marked Amino Metabolism Modifications and an Increase in TMZ Sensitivity in Hs683 Oligodendroglioma Cells

Gliomas account for more than 50% of all primary brain tumors. The worst prognosis is associated with gliomas of astrocytic origin, whereas gliomas with an oligodendroglial origin offer higher sensitivity to chemotherapy, especially when oligodendroglioma cells display 1p19q deletions. Temozolomide...

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Main Authors: Lamoral-Theys, Delphine, Le Mercier, Marie, Le Calvé, Benjamin, Rynkowski, Michal A, Bruyère, Céline, Decaestecker, Christine, Haibe-Kains, Benjamin, Bontempi, Gianluca, Dubois, Jacques, Lefranc, Florence, Kiss, Robert
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805885/
https://ncbi.nlm.nih.gov/pubmed/20072655
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