Ligand-Specific Function of Transforming Growth Factor Beta in Epithelial-Mesenchymal Transition in Heart Development

The ligand specificity of transforming growth factor beta (TGFβ) in vivo in mouse cardiac cushion epithelial-to-mesenchymal transition (EMT) is poorly understood. To elucidate the function of TGFβ in cushion EMT, we analyzed Tgfb1 (−/−), Tgfb2(−/−) and Tgfb3(−/−) mice between embryonic day (E) 9.5 a...

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Bibliografiske detaljer
Main Authors: Azhar, Mohamad, Runyan, Raymond B., Gard, Connie, Sanford, L. Philip, Miller, Marian L., Andringa, Anastasia, Pawlowski, Sharon, Rajan, Sudarsan, Doetschman, Tom
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805850/
https://ncbi.nlm.nih.gov/pubmed/19161227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21854
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