The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in the regulation of multiple cellular pathways, such as xenobiotic metabolism and Th17 cell differentiation. Identification of key physiologically relevant ligand(s) that regulate AHR function remains to be acco...

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Autors principals: Schroeder, Jennifer C., DiNatale, Brett C., Murray, Iain A., Flaveny, Colin A., Liu, Qiang, Laurenzana, Elizabeth M., Lin, Jyh Ming, Strom, Stephen C., Omiecinski, Curtis J., Amin, Shantu, Perdew, Gary H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805781/
https://ncbi.nlm.nih.gov/pubmed/20000589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901786x
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