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Enthalpy-entropy Contribution to Carcinogen-induced DNA Conformational Heterogeneity
DNA damage by adduct formation is a critical step for the initiation of carcinogenesis. Aromatic amines are strong inducers of environmental carcinogenesis. Their DNA adducts are known to exist in an equilibrium between the major groove (B) and base-displaced stacked (S) conformations. However, the...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805757/ https://ncbi.nlm.nih.gov/pubmed/19961237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901629p |
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