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Mutations in the genes coding for the NF-κB regulating factors IκBα and A20 are uncommon in nodular lymphocyte-predominant Hodgkin’s lymphoma

Nodular lymphocyte-predominant Hodgkin’s lymphoma (NLPHL) shows constitutive NF-κB activity in the malignant lymphocyte-predominant (LP) cells. Constitutive NF-κB activity also plays a central pathogenetic role in classical Hodgkin’s lymphoma (cHL), where inactivating mutations in the NFKBIA and TNF...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Schumacher, Martin A., Schmitz, Roland, Brune, Verena, Tiacci, Enrico, Döring, Claudia, Hansmann, Martin-Leo, Siebert, Reiner, Küppers, Ralf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ferrata Storti Foundation 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805741/
https://ncbi.nlm.nih.gov/pubmed/19648161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.010157
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