Mutations in the genes coding for the NF-κB regulating factors IκBα and A20 are uncommon in nodular lymphocyte-predominant Hodgkin’s lymphoma

Nodular lymphocyte-predominant Hodgkin’s lymphoma (NLPHL) shows constitutive NF-κB activity in the malignant lymphocyte-predominant (LP) cells. Constitutive NF-κB activity also plays a central pathogenetic role in classical Hodgkin’s lymphoma (cHL), where inactivating mutations in the NFKBIA and TNF...

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Detalhes bibliográficos
Main Authors: Schumacher, Martin A., Schmitz, Roland, Brune, Verena, Tiacci, Enrico, Döring, Claudia, Hansmann, Martin-Leo, Siebert, Reiner, Küppers, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805741/
https://ncbi.nlm.nih.gov/pubmed/19648161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.010157
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