Frequency and clinical relevance of DNA microsatellite alterations of the CDKN2A/B, ATM and p53 gene loci: a comparison between pediatric precursor T-cell lymphoblastic lymphoma and T-cell lymphoblastic leukemia

Although deletions of cell cycle regulatory gene loci have long been reported in various malignancies, little is known regarding their relevance in pediatric T-cell lymphoblastic lymphoma (T-LBL) and T-cell lymphoblastic leukemia (TALL). The current study focused on loss of heterozygosity (LOH) anal...

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Bibliographic Details
Main Authors: Krieger, David, Moericke, Anja, Oschlies, Ilske, Zimmermann, Martin, Schrappe, Martin, Reiter, Alfred, Burkhardt, Birgit
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2010
Subjects:
Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805736/
https://ncbi.nlm.nih.gov/pubmed/19586936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.007526
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