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An efficient algorithm for the stochastic simulation of the hybridization of DNA to microarrays

BACKGROUND: Although oligonucleotide microarray technology is ubiquitous in genomic research, reproducibility and standardization of expression measurements still concern many researchers. Cross-hybridization between microarray probes and non-target ssDNA has been implicated as a primary factor in s...

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Main Authors: Arslan, Erdem, Laurenzi, Ian J
格式: Artigo
語言:Inglês
出版: BioMed Central 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805644/
https://ncbi.nlm.nih.gov/pubmed/20003312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-411
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