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Purification and subunit structure of a putative K+-channel protein identified by its binding properties for dendrotoxin I.

The binding protein for the K+-channel toxin dendrotoxin I was purified from a detergent extract of rat brain membranes. The purification procedure utilized chromatography on DEAE-Trisacryl, affinity chromatography on a dendrotoxin-I-Aca 22 column, and wheat germ agglutinin-Affigel 10 with a final 3...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rehm, H, Lazdunski, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280549/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2455300/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4919
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