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Effect of Short-Term Free Fatty Acids Elevation on Mitochondrial Function in Skeletal Muscle of Healthy Individuals

Context: Mitochondrial dysfunction has been proposed as an underlying mechanism in the pathogenesis of insulin resistance and type 2 diabetes mellitus. Objective: To determine whether mitochondrial dysfunction plays a role in the free fatty acid (FFA)-induced impairment in insulin action in skeletal...

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Bibliographische Detailangaben
Hauptverfasser: Chavez, Alberto O., Kamath, Subhash, Jani, Rucha, Sharma, Lokendra K., Monroy, Adriana, Abdul-Ghani, Muhammad A., Centonze, Victoria E., Sathyanarayana, Padma, Coletta, Dawn K., Jenkinson, Cristopher P., Bai, Yidong, Folli, Franco, DeFronzo, Ralph A., Tripathy, Devjit
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Endocrine Society 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805487/
https://ncbi.nlm.nih.gov/pubmed/19864449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-1387
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