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Glycosylation of Therapeutic Proteins: An Effective Strategy to Optimize Efficacy

During their development and administration, protein-based drugs routinely display suboptimum therapeutic efficacies due to their poor physicochemical and pharmacological properties. These innate liabilities have driven the development of molecular level strategies to improve the therapeutic behavio...

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Hlavní autoři: Solá, Ricardo J., Griebenow, Kai
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805475/
https://ncbi.nlm.nih.gov/pubmed/20055529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/11530550-000000000-00000
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