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Ligand-specific regulation of the extracellular surface of a G protein coupled receptor
G protein coupled receptors (GPCRs) are seven transmembrane proteins that mediate the majority of cellular responses to hormones and neurotransmitters. They are the largest group of therapeutic targets for a broad spectrum of diseases. Recent crystal structures of GPCRs1,2,3,4,5 reveal structural co...
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| Auteurs principaux: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805469/ https://ncbi.nlm.nih.gov/pubmed/20054398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08650 |
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