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Microsecond molecular dynamics simulation shows effect of slow loop dynamics on backbone amide order parameters of proteins

A molecular-level understanding of the function of a protein requires knowledge of both its structural and dynamical properties. NMR spectroscopy allows the measurement of generalized order parameters that provide an atomistic description of picosecond and nanosecond fluctuations in protein structur...

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Detalles Bibliográficos
Main Authors: Maragakis, Paul, Lindorff-Larsen, Kresten, Eastwood, Michael P., Dror, Ron O., Klepeis, John L., Arkin, Isaiah T., Jensen, Morten Ø., Xu, Huafeng, Trbovic, Nikola, Friesner, Richard A., Palmer, Arthur G., Shaw, David E.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805408/
https://ncbi.nlm.nih.gov/pubmed/18311962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp077018h
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