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Systematic Validation of Protein Force Fields against Experimental Data

Molecular dynamics simulations provide a vehicle for capturing the structures, motions, and interactions of biological macromolecules in full atomic detail. The accuracy of such simulations, however, is critically dependent on the force field—the mathematical model used to approximate the atomic-lev...

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Bibliografische gegevens
Hoofdauteurs: Lindorff-Larsen, Kresten, Maragakis, Paul, Piana, Stefano, Eastwood, Michael P., Dror, Ron O., Shaw, David E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285199/
https://ncbi.nlm.nih.gov/pubmed/22384157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032131
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