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Rosiglitazone activation of PPARγ suppresses fractalkine signaling

The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) is a key transcriptional regulator of both lipid metabolism and inflammation. The importance of PPARγ is accentuated by the widespread use of synthetic PPARγ agonists, thiazolidinediones (such as rosiglitazone), as drugs for i...

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Main Authors: Wan, Yihong, Evans, Ronald M
格式: Artigo
語言:Inglês
出版: Society for Endocrinology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805405/
https://ncbi.nlm.nih.gov/pubmed/19850645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-09-0090
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