Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.

Achieving the capacity to detect minimal numbers of neoplastic cells is a major cancer diagnostic challenge. Chromosomal translocations such as the t(14;18)(q32;q21) found in follicular and some nonfollicular lymphomas provide a tumor-specific molecular marker. The 14;18 breakpoints are focused at o...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Crescenzi, M, Seto, M, Herzig, G P, Weiss, P D, Griffith, R C, Korsmeyer, S J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3133663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4869
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