Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.

Achieving the capacity to detect minimal numbers of neoplastic cells is a major cancer diagnostic challenge. Chromosomal translocations such as the t(14;18)(q32;q21) found in follicular and some nonfollicular lymphomas provide a tumor-specific molecular marker. The 14;18 breakpoints are focused at o...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Crescenzi, M, Seto, M, Herzig, G P, Weiss, P D, Griffith, R C, Korsmeyer, S J
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1988
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280538/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3133663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4869
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