Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats

To explore the specific contribution of the C1 neurons to blood pressure (BP) control, we used an optogenetic approach to activate these cells in vivo. A lentivirus that expresses channelrhodopsin-2 (ChR2) under the control of the catecholaminergic neuron-preferring promoter PRSx8 was introduced int...

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Autores principales: Abbott, Stephen B G, Stornetta, Ruth L, Socolovsky, Carmela S, West, Gavin H, Guyenet, Patrice G
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2009
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805374/
https://ncbi.nlm.nih.gov/pubmed/19822543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.177535
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