Circulating complexes containing IgA and fibronectin in patients with primary IgA nephropathy.

IgA antibodies from patients with primary IgA nephropathy bind to collagens I, II, and IV. Here we show that this binding is mediated by the collagen-binding site of fibronectin, which occurs in the circulation in complex with IgA. No antibodies binding directly to collagen were identified. The comp...

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Autores principales: Cederholm, B, Wieslander, J, Bygren, P, Heinegård, D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC280537/
https://ncbi.nlm.nih.gov/pubmed/3387443
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