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Circulating complexes containing IgA and fibronectin in patients with primary IgA nephropathy.

IgA antibodies from patients with primary IgA nephropathy bind to collagens I, II, and IV. Here we show that this binding is mediated by the collagen-binding site of fibronectin, which occurs in the circulation in complex with IgA. No antibodies binding directly to collagen were identified. The comp...

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Bibliografiske detaljer
Main Authors: Cederholm, B, Wieslander, J, Bygren, P, Heinegård, D
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC280537/
https://ncbi.nlm.nih.gov/pubmed/3387443
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