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rRNA Mutations That Inhibit Transfer-Messenger RNA Activity on Stalled Ribosomes
In eubacteria, stalled ribosomes are rescued by a conserved quality-control mechanism involving transfer-messenger RNA (tmRNA) and its protein partner, SmpB. Mimicking a tRNA, tmRNA enters stalled ribosomes, adds Ala to the nascent polypeptide, and serves as a template to encode a short peptide that...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805313/ https://ncbi.nlm.nih.gov/pubmed/19897649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01178-09 |
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