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The BosR regulatory protein of Borrelia burgdorferi interfaces with the RpoS regulatory pathway and modulates both the oxidative stress response and pathogenic properties of the Lyme disease spirochete

Borrelia burgdorferi, the Lyme disease spirochete, adapts as it moves between the arthropod and mammalian hosts that it infects. We hypothesize that BosR serves as a global regulator in B. burgdorferi to modulate the oxidative stress response and adapt to mammalian hosts. To test this hypothesis, a...

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Autores principales: Hyde, Jenny A., Shaw, Dana K., Smith, Roger, Trzeciakowski, Jerome P., Skare, Jon T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805275/
https://ncbi.nlm.nih.gov/pubmed/19906179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06951.x
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