Complement Evasion by Lyme Disease Spirochetes

Por Skare, Jon T., Garcia, Brandon L.
Publicado no Trends Microbiol (2020)

The Classical Complement Pathway Is Required to Control Borrelia burgdorferi Levels During Experimental Infection

Por Zhi, Hui, Xie, Jialei, Skare, Jon T.
Publicado no Front Immunol (2018)

The BB0646 protein demonstrates lipase and hemolytic activity associated with Borrelia burgdorferi, the aetiological agent of Lyme disease

Por Shaw, Dana K., Hyde, Jenny A., Skare, Jon T.
Publicado em 2011

Genetic Manipulation of Borrelia burgdorferi

Por Hyde, Jenny A., Weening, Eric H., Skare, Jon T.
Publicado em 2011

Live Imaging

Por Chaconas, George, Moriarty, Tara J., Skare, Jon, Hyde, Jenny A.
Publicado no Curr Issues Mol Biol (2020)

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex

Por Garcia, Brandon L., Zhi, Hui, Wager, Beau, Höök, Magnus, Skare, Jon T.
Publicado no PLoS Pathog (2016)

Invasion of Eukaryotic Cells by Borrelia burgdorferi Requires β(1) Integrins and Src Kinase Activity

Por Wu, Jing, Weening, Eric H., Faske, Jennifer B., Höök, Magnus, Skare, Jon T.
Publicado em 2011

BB0744 Affects Tissue Tropism and Spatial Distribution of Borrelia burgdorferi

Por Wager, Beau, Shaw, Dana K., Groshong, Ashley M., Blevins, Jon S., Skare, Jon T.
Publicado no Infect Immun (2015)

Characterization of a Conditional bosR Mutant in Borrelia burgdorferi

Por Hyde, Jenny A., Shaw, Dana K., Smith, Roger, Trzeciakowski, Jerome P., Skare, Jon T.
Publicado em 2010

The BosR regulatory protein of Borrelia burgdorferi interfaces with the RpoS regulatory pathway and modulates both the oxidative stress response and pathogenic properties of the Ly...

Por Hyde, Jenny A., Shaw, Dana K., Smith, Roger, Trzeciakowski, Jerome P., Skare, Jon T.
Publicado em 2009

Analysis of Mechanisms Associated with Loss of Infectivity of Clonal Populations of Borrelia burgdorferi B31MI

Por McDowell, John V., Sung, Shian Ying, Labandeira-Rey, Maria, Skare, Jon T., Marconi, Richard T.
Publicado em 2001

Structural determination of the complement inhibitory domain of Borrelia burgdorferi BBK32 provides insight into classical pathway complement evasion by Lyme disease spirochetes

Por Xie, Jialei, Zhi, Hui, Garrigues, Ryan J., Keightley, Andrew, Garcia, Brandon L., Skare, Jon T.
Publicado no PLoS Pathog (2019)

The BBA33 lipoprotein binds collagen and impacts Borrelia burgdorferi pathogenesis

Por Zhi, Hui, Weening, Eric H., Barbu, Elena Magda, Hyde, Jenny A., Höök, Magnus, Skare, Jon T.
Publicado no Mol Microbiol (2015)

Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin binding protein BBK32 is required for optimal infectivity

Por Hyde, Jenny A., Weening, Eric H., Chang, MiHee, Trzeciakowski, Jerome P., Höök, Magnus, Cirillo, Jeffrey D., Skare, Jon T.
Publicado em 2011

The intergenic small non-coding RNA ittA is required for optimal infectivity and tissue tropism in Borrelia burgdorferi

Por Medina-Pérez, Diana N., Wager, Beau, Troy, Erin, Gao, Lihui, Norris, Steven J., Lin, Tao, Hu, Linden, Hyde, Jenny A., Lybecker, Meghan, Skare, Jon T.
Publicado no PLoS Pathog (2020)

A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species

Por Ramsey, Meghan E., Hyde, Jenny A., Medina-Perez, Diana N., Lin, Tao, Gao, Lihui, Lundt, Maureen E., Li, Xin, Norris, Steven J., Skare, Jon T., Hu, Linden T.
Publicado no PLoS Pathog (2017)

Genome-wide screen identifies novel genes required for Borrelia burgdorferi survival in its Ixodes tick vector

Por Phelan, James P., Kern, Aurelie, Ramsey, Meghan E., Lundt, Maureen E., Sharma, Bijaya, Lin, Tao, Gao, Lihui, Norris, Steven J., Hyde, Jenny A., Skare, Jon T., Hu, Linden T.
Publicado no PLoS Pathog (2019)

Biomechanics of Borrelia burgdorferi Vascular Interactions

Por Ebady, Rhodaba, Niddam, Alexandra F., Boczula, Anna E., Kim, Yae Ram, Gupta, Nupur, Tang, Tian Tian, Odisho, Tanya, Zhi, Hui, Simmons, Craig A., Skare, Jon T., Moriarty, Tara J.
Publicado no Cell Rep (2016)

Profiling of Temperature-Induced Changes in Borrelia burgdorferi Gene Expression by Using Whole Genome Arrays

Por Ojaimi, Caroline, Brooks, Chad, Casjens, Sherwood, Rosa, Patricia, Elias, Abdallah, Barbour, Alan, Jasinskas, Algis, Benach, Jorge, Katona, Laura, Radolf, Justin, Caimano, Melissa, Skare, Jon, Swingle, Kristen, Akins, Darrin, Schwartz, Ira
Publicado em 2003

Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules

Por Moriarty, Tara J., Shi, Meiqing, Lin, Yi-Pin, Ebady, Rhodaba, Zhou, Hong, Odisho, Tanya, Hardy, Pierre-Olivier, Salman-Dilgimen, Aydan, Wu, Jing, Weening, Eric H., Skare, Jon T., Kubes, Paul, Leong, John, Chaconas, George
Publicado em 2012