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Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication

Prohibitin, a tumor suppressor protein, has been shown to repress E2F-mediated transcription and arrest cell cycle progression. While prohibitin has been proposed to regulate cell cycle progression by repressing transcriptional targets of E2F1, it is not clear whether other mechanisms are also invol...

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Main Authors: Rizwani, Wasia, Alexandrow, Mark, Chellappan, Srikumar
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805263/
https://ncbi.nlm.nih.gov/pubmed/19377303
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