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Amplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules.

Amplification of genes can sometimes be detected by molecular hybridization but not by cytogenetic methods, suggesting that in some cases the units of amplification may be too small to be detected by light microscopy. The experiments reported here investigate whether submicroscopic amplification uni...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Von Hoff, D D, Needham-VanDevanter, D R, Yucel, J, Windle, B E, Wahl, G M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280524/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3164477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4804
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