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Haplotype Analysis of CYP11A1 Identifies Promoter Variants Associated with Breast Cancer Risk

The CYP11A1 gene encodes the cholesterol side chain cleavage enzyme that catalyzes the initial and rate-limiting step of steroidogenesis. A large number of epidemiological studies have implicated the duration and degree of endogenous estrogen exposure in the development of breast cancer in women. He...

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Bibliographic Details
Main Authors: Yaspan, Brian L., Breyer, Joan P., Cai, Qiuyin, Dai, Qi, Elmore, J. Bradford, Amundson, Isaac, Bradley, Kevin M., Shu, Xiao-Ou, Gao, Yu-Tang, Dupont, William D., Zheng, Wei, Smith, Jeffrey R.
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805128/
https://ncbi.nlm.nih.gov/pubmed/17575134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-0467
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